Warnings and Precautions
This medication must only be administered directly into a vein. If it accidentally leaks into muscle or skin, severe damage can result. Infrequently, serious heart problems can result, including heart failure. If a patient experiences irregular heartbeat, sudden weight gain, shortness of breath, or feet/ankle swelling they must notify their doctor immediately.
In very rare cases, a new cancer, such as secondary leukemia, may develop in those using this medication. When this medication is combined with radiation therapy of certain other anti-cancer drugs, this rare complication is possible.
Before surgery or dental treatment, notify the health care provider. Those who are breastfeeding or pregnant must avoid this drug. Women must also not get pregnant when using this medication. Patients must talk to their doctor before getting any immunizations or vaccinations and must avoid contact with those who have had a recent influenza or polio vaccine. Patients must also be very careful to not get bruises, cuts, or other injuries.