Do Motrin and Robitussin Cause Heart Attacks When Combined in Children?

Article by Robyn Broyles (11,581 pts )
Edited & published by Leigh A. Zaykoski (7,600 pts ) on Nov 6, 2009

Many people have read a message, widely circulated recently on the Internet, that an 8-year-old girl died of a heart attack caused by the combination of Motrin and Robitussin. The message asserts that "quite a few children" have died the same way. But is it true?

Ingredients of Motrin and Robitussin

The active ingredient of all Children's Motrin products is ibuprofen. Robitussin has two products for children with different active ingredients. The active ingredient of Children's Robitussin "Stubborn Cough" DM is dextromethorphan, while the active ingredients of Children's Robitussin Cough and Cold are dextromethorphan and pseudoephedrine.

The FDA has issued no warnings (none, zero) about interactions among these three drugs. There is no evidence that ibuprofen, dextromethorphan, or pseudoephedrine can cause heart attacks in children or adults when combined.

It is possible for a person, whether child or adult, to have an allergic reaction to an ingredient in a medication. The reaction could include anaphylaxis, which can result in loss of blood pressure, tachycardia (increased heart rate), breathing trouble, and sudden death. An anaphylactic reaction would most likely result from an allergy to a single ingredient, in which case it not be made more likely by combining medications.

Is it Safe to Mix Robitussin and Motrin?

One version of the e-mail was sent from an employee at a large children's hospital. I contacted the hospital's public relations department to ask about the story. I received a response saying that the e-mail forward was not an official e-mail from the hospital; it also said,

"The patient described in the forward was not a patient at [our hospital], and to the best of our knowledge, the information is not accurate. However, our physicians encourage consulting your child's care provider or a pharmarcist before mixing OTC medications."

In other words, there is no reason to think that mixing these particular medicines is dangerous when the correct dosing is used, although prudence suggests checking with a professional first.

Dangers of Mixing Medications

Although this story is almost certainly a hoax, there is truth to the idea that it can be dangerous to mix over-the-counter medications. Many cough and cold products contain multiple ingredients. If a parent gives multiple medicines to their child and does not pay close attention to the ingredients, they could give the child an overdose of one or more ingredients. An overdose can be dangerous or even fatal, especially with antihistamines, which are central nervous system depressants and can cause breathing to stop.

Always follow the dosage instructions for any over-the-counter medication, and do not give medicine more often than directed. Also, follow the age ranges as directed; do not give a product to a child younger than instructed on the label. Pay attention to ingredients to avoid doubling up. If you follow these guidelines, and check with a doctor, nurse, or pharmacist before mixing different products, you and your child can feel safe in taking OTC medicines.

The information in this article should not be considered medical advice. The information in this article is not meant to treat, diagnose, prescribe or cure any ailment. Always check with your physician before taking any products or following any advice you have read on Brighthub.com.

Comments

Nov 27, 2009 4:21 AM
SCROCKET316
Fear Hoaxes = Terrorism
These types of internet hoaxes should be considered forms of terrorism and the originators of such gargage should be tracked down and convicted....it's nothing more than terrorism at it's most basic form.
Nov 23, 2009 3:09 PM
Scott Strosahl
Yup, you're right...
@Can't Stand Hoaxes
Yup, Investi-Gator.com also confirms it...
http://www.investi-gator.com/2009/11/is-it-dangerous-to-mix-robitussin-and.html
Nov 16, 2009 1:20 PM
Checking up
To "Can't Stand Hoaxes," I feel that way about chain emails, too. At least these two medications don't need to be combined to save lives, so little harm is done, but I hate to see misinformation gaining a foothold.
Nov 16, 2009 10:32 AM
Cantstand Hoaxes
I can't stand a hoax
I agree completely Glenda. This is how mass hysteria starts. Now, there are untold numbers of people who won't mix these two medications because they think they'll kill someone. And as easy as it is, no one bothers to check the validity of emails. I've asked all my contacts several times to please do their homework before sending me crap mail.. and still I get stuff like this. The buck always stops at my doorstep.
Nov 6, 2009 9:30 AM
Glenda
Info on Snopes
Good source,Robyn. Stephanie, you must not've searched too hard, I pulled it up the first time. There is a long explanation since 2/09. However, Truth or Fiction did not come up with anything when I searched "Robitussin and Motrin" there. I rec'd this same email and always verify these speculative emails on either snopes or TOF or both. I wish people would check the truth of these emails out before they pass along false information.
Nov 5, 2009 7:58 PM
Thanks
Thanks for the feedback. I'm glad it has been helpful to people. The main danger of mixing these medications is overdose, as I pointed out in the article. The best precaution is to read the labels diligently to avoid double doses.

I've heard of some studies suggesting dextromethorphan, the main ingredient in Robitussin DM, is not actually very effective. I haven't reviewed those studies, though.
Nov 5, 2009 6:10 PM
Sherri
You set the record straight!
Putting it out in plain English. It all makes sense. I despise internet hoaxes. I'm not a big fan of cough syrups anyway, but fear hoaxes are the worst.
Oct 20, 2009 2:20 PM
Renee
Geat insight for parents!
I am very greatful for the information. It is always important to read labels and also expirations dates of medicines. also coughing is a defense mechanism and should not always be imparied by medication. only if it keeps you awake at night should it be prescirbed. Thanks
Jun 17, 2009 9:15 AM
Stephanie Olson
Great article!
This is a great article. I appreciate your research on this one...I couldn't find it anywhere on snopes.

Thank you!