Different Types of Ehlers-Danlos Syndrome
The six different types of Ehlers-Danlos syndrome, which are listed below, either follow an autosomal dominant or autosomal recessive pattern of inheritance. Autosomal dominant means that only one of the two copies of a faulty gene needs to be inherited for a person to contract the condition. Autosomal recessive means that both faulty copies have to be inherited for a person to be affected by the condition.
Hypermobility - the most common form of the disease. Hypermobility affects elbow and knee joints, and smaller joints in fingers and toes. Chronic joint pain is another symptom. Skin bruises easily. Hypermobility follows an autosomal dominant pattern of inheritance.
Classical - the skin is smooth and stretchy, and joints are hyperextensible, meaning they can sprain and dislocate easily. Hernias are another complication with this type of Ehlers-Danlos syndrome. Classical follows an autosomal dominant pattern of inheritance.
Vascular - this is the most serious form of the condition. Skin is translucent, veins can be seen, and there is extensive bruising. Joint hypermobilty is usually found in the digits, and what makes the vascular form so severe is that there could be arterial or organ rupture. Vascular follows an autosomal dominant pattern of inheritance.
Arthrochalasia - a rare type where congenital hip dislocation is the major complication. Other symptoms include easy bruising and severe joint hypermobility. Dislocations are common. Arthrochalasia follows an autosomal dominant pattern of inheritance.
Dermatosparaxis - another rare type. Symptoms include extremely fragile skin with easy bruising. Individuals may also experience large hernias. Dermatosparaxis follows an autosomal recessive pattern of inheritance.
Kyphoscoliosis - also a rare form of the condition. There is a general laxity of the joints, and eyes and skin are fragile. Individuals can lose the ability to walk by their second or third decade. Kyphoscoliosis follows an autosomal recessive pattern of inheritance.