Here are some things you can do to make your experience with netbooks more enjoyable. 
1. Don't upgrade the operating system
Unless it's necessary, upgrading the embedded OS is not advisable. You can, however, downgrade it to gain some increase in performance. Since netbooks are designed for ultra-portable computing, they are not equipped with the fastest processor. So, downgrading from Vista to XP - for example - can give a performance boost.
2. Invest in a good laptop bag
Yes, I know you already got the matching sleeves when you purchased the machine. However, it can't accommodate your charger and other accessories that I mention next. Sure, it will still be useful for light traveling, but if you're really serious in making it your day-to-day companion, a decent laptop bag is the way to go. Since the market is pretty big now, well-known laptop bag manufacturers will already have specific models for netbooks. As an alternative, you can opt for 12-inch laptop bags.
3. Buy a bigger capacity or secondary battery
A higher capacity battery may not be for everyone; however if you do much traveling, it's a blessing. If you don't like the fact that you're shelling out more cash, select the model with a hi-cap battery which can last around 4-6 hours. Do remember that extended batteries sometimes protrude from the body, so netbook sleeves may not be able to be used. See no.2 for the solution.
4. Set up a bigger monitor for home use
The screen size in netbook ranges from seven to ten inches, and that's pretty small. If you often use the netbook at home or at the office, setting up an bigger external monitor is a good idea. Your eyes will thank you for that.
5. Don't run a lot of applications in the background
Netbooks are made for ultimate portability and aimed to be a second computer, so it's very different than your average desktop PC. Of course it's good to have all the applications that you usually have in the desktop here. However, it will put a toll in the performance. Be more selective and choose which apps run in the background, or uninstall ones that you rarely use.
