The Comodo SecureEmail help file is located in the program folder and can be launched from the GUI; the well written content is of reasonable length and resembles the user guide which can be downloaded from the vendor’s website, where further information can be found in the Knowledge Base and the forum.
As can be derived from the section Installation and Setup I had some difficulties (I am using Firefox as default browser, and the free POP/SMTP email accounts I had set up for testing Comodo Secure Email 2.0 were unreliable) which made me turn to contact Comodo support. Their support responded quickly, and their advice was helpful.