Ergonomics and Durability
Asus is good at being innovative with its design, form, and layout. Case in point, they created the first netbook but they haven't stopped there. A few months ago I was convinced I wanted an Acer netbook, the layout was comparable, the screen better, and the form a little nicer on the Acer. But then Asus came out with a new model and blew me away. They replaced the traditional touchpad with a textured surface that works brilliantly, moved a one button mouse (still works as a right and left click, it's just one button), and replaced the screen with a much nicer glass one. Also, they flattened out the keys (so that they no longer have the traditional pyramid-like rise) making it far easier for those of us with larger fingers to type on the little netbook.
I expect that Asus will continue to innovate like this but the innovations they have already instituted are enough to go ahead and take a look at. Their laptops tend to be slick and well formed with a nice finish. They all come with a built-in webcam and with the sort of functions that make using a laptop easier, such as the button to turn off the keypad (I can't tell you how helpful this is when trying to type on it).
As far as durability goes, their larger laptops are definitely a lot more sturdy than the netbooks. However, I think that the netbooks are less durable because they are small and tend to get thrown around a bit more because of it. Keep in mind that all laptops are rather easily damaged. However, I find that even my netbook has a form factor that is in many ways more durable than my previous laptop, which was a Dell.