The gameplay in Real Estate Empire 2 is pretty good for casual time management games. There are several different levels, and each level has three different difficulties that you can try your skills at - which I really liked. Once you beat a level, you can always go back and replay it on a harder difficulty, upping the replay value of the game. Now, the lower levels are pretty easy as you're learning the ropes of the game itself. Once you get past those first couple of levels, the game gets harder, even on the easy mode. I personally like this touch, as I prefer to have a challenge to get past, not just an easy ride through the game.
I do like the fact that each different section of the game has several different levels in it, and each of these can be played on any of the three different difficulties. As you get toward the last few levels, the game gets hard enough that you really have to stop and think before you make a move so you don't mess up later on. And, the overall gameplay is pretty diverse, as you go from nice quiet neighborhoods to the Big Apple to a trailer park and so on. It makes the game interesting.
The basic principle in the gameplay is simple: earn money and complete your goals. Each level has different goals, such as own four houses, have three 5-star houses, have six renters with good or better history, and so on. You also have a "Hurry Month" button so that you can get the month over quicker, pay your bills, take in rent, and so on. But, I found that this can also hurt you if you use it too much.
One thing I didn't like about the gameplay is that the map is small. I personally like a huge game board where there are more than enough houses or buildings to buy up instead of just ten or so. So, I do wish that the developers had made each level a bit bigger, but it's not a deal breaker for me as the gameplay is good.