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Random Events
Every turn, the Galactic news will pop-up and deliver random events, which can give a huge advantage to a given race or cause problems for all the races. Space-warps can render lightspeed impossible for several rounds, while a famine can break out on your best colony and decimate it.
Rarer random events are in the game as well, but you just have to play a while to find those. They include funny news reports, population booms, and mutation (which in turn helps development).
Leaders
Throughout the game, you will be contacted by various characters with specific skills you can hire to run colonies and help pilot your ships. These leaders will range all over the place in ability and price, so you are forced to take who you hire seriously, because a bad leader can kill your whole game.
Large-Scale Space Combat
We're talking hundreds of ships doing battle. At the beginning of the game you get to choose whether you want to actually control the ships (Tactical mode) or let them be controlled by the computer (Strategic mode). It is worth pointing out that Strategic mode means you can't design ships and that if you choose Tactical you can choose to let a battle be fought by the computer. I thus recommend Tactical mode.
Spies
The final and coolest aspect of the game is espionage. Players can transform their units into special units who can then be sent out to gather information on the other races or commit sabotage. It is worth noting that I have won the game through sabotage. Spies can steal technologies as well, so placing at least a few of them early on in your race's development can speed up your race's development.