You need to hire a range of staff, including builders to construct your new buildings and sets and maintain existing ones as well as janitors to keep the studio looking nice and clean. Of course you'll need scriptwriters, actors and actresses, a crew, directors and even scientists to research new options for sets, scenes, props and costumes.
Staff can be given raises, and your acting and directing talent have to be nurtured and moulded if you want them to pick up awards at the periodic awards ceremonies. Each of your actors and directors have personality traits which can make them a real handful to deal with. While it is tempting to allow them to blow off steam by downing a few at the bar after a shoot, it can lead to alcoholism and frequent absences, which unfortunately eats into your production schedule. You can also choose clothes for your stars, develop their relationships with each other, and even send them for a spot of plastic surgery.