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In the Select Playable Nations you need to select which nation you wish to be a manager in. Larger PC's with fast CPUs and plenty of RAM will happily get away with letting you choose as many as you like, but for the best performance you should only choose one or two.
Once this choice is made, it is time to name your manager, choose a nationality, date of birth and Favorite Club. This can prove important later in the game if you choose to manage your favorite club.
Complete all fields and click Next to move beyond this screen; it's time to pick the club to manage from the leagues of the nation you picked earlier. Each team you pick will have certain information attached, such as transfer budget, wage budget, average attendance - all vital information for deciding whether to choose to manage the team or not.
At the top of this screen are two tabs - Club and Nation. It is possible to manage both a football club and a national side, although there is no compulsion to manage a national team at this stage in the game.
When you have picked your team(s), click Next to move onto the Manager Status screen. Your manager will be created and the game set up.