Pulse Grenade/Mine - AOE 1+10 Radius 450 - The pulse grenade does very little damage against biological enemies, but it receives a +200 damage bonus against machines. This makes it much more powerful than most mines and grenades, and ideal for use against robots. There is one exception to this however; if used to level up the Demolition Expert perk, Plasma Explosives do more damage against machines than Pulse Explosives. This is because the bonus from Demolition Expert doesn't seem to affect the bonus damage that Pulse Explosives do against machines.
Frag Grenade/Mine - AOE 1+100 Radius 450/192 - The most common form of Explosive in the Wasteland, these handy and plentiful devices do significant damage to enemies, particularly when they are bundled up. Frag Explosives are not deadly enough to be real boss-killers, but they are very good at weakening or slaying a tight-knit group of moderately powerful enemies. The biggest downside to these is that they become heavy when carried in bulk. Note that the Mine version of this Explosive has a smaller AOE than the grenade.
Plasma Grenade/Mine - AOE 1+150 Radius 450/192 - More expensive and far less common that Frag Explosives, Plasma Explosives up the damage by 33%. Obviously, this makes Plasma Explosives much more deadly than their Frag counter-parts, but it still isn't always enough to crack really tough targets. This - combined with their relative rarity - make Plasma Explosives less useful than you'd expect. They are great at clearing out groups of enemies, but you encounter these Explosives so rarely that you never seem to have one when you need it. Note that the Mine version of this Explosive has a smaller AOE than the grenade.
Nuka Grenades - AOE 1+500 Radius 450 - The Nuke Grenade is kind of like a hand-held Fat Man. If that sounds deadly, that's because it is. These are an extremely good grenade to use if you need something to die, and die quickly. On the downside, these are schematic built, which means you'll have to conserve them for use against difficult enemies.
Bottlecap Mine - AOE 1+500 Radious 256 - Bottlecap Mines are kind of like the mine equivalent of the Nuke Grenade. They do the same amount of damage, and they are also built from schematics. That said, the Nuke Grenade and the Bottlecap Mine tend to shine in opposite situations. Nuka Grenades are great outdoors, where their tendency to bounce, their mid-long range, and their higher blast radius are useful. On the other hand, Bottlecap Mines are better indoors, where having a big blast radius and an unpredictable flight pattern are downsides. A Bottlecap Mine can be laid down exactly where you want it, and since you're indoors, you don't have to worry as much about an enemy going around it.