Out into the Wasteland
The basic premise of the story is tried and true Fallout: Independence and the outside world are thrust upon you for one reason or another and you are left to sort out what you ultimately do. The big difference is that this time it is for personal reasons rather than some "for the greater good" motive. This gives your character a much more open venue to take care of things as you wish. I also like the fact that you get to participate in small parts of your life before adulthood.
Bethesda always seems to do a good job including side quests that have some value to them. If you only do the main quest you end up missing at least ninety percent of the game, not to mention there are a multitude of places to explore and loot. Pick up this game, and you are in for an expansive list of possible things to do.
I Feel Like Taking a Walk
Travel is much like The Elder Scrolls IV: Oblivion where, via the overhead map, if you have been there before, you can immediately travel to the place you want to go using the "fast travel" system. I am a little sad to have the fear of random encounters when you are fast traveling. Random encounters are still there when you first have to discover an area though so I can't complain too much.
Not being great at First Person type games, I can say that the VATS system is an extremely welcome part of the Fallout 3 battle system. For your information, VATS stands for Vault-Tec Assisted Targeting System. It allows you to stop the action and use your action points to target a specific area of an enemy's body. I have to say that it is a genius way to keep fans of the turn-based targeting system of previous Fallout games from going ballistic.