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Sometimes a pistol simply isn't enough, you need the most powerful of the Red Dead Redemption Weapons, the rifles. There are seven different rifles to unlock, ranging from the powerful Buffalo Rifle to the classic western standby, the Winchester Repeater.
To unlock the Bolt Action Rifle, you must first complete the "The Gates of El Presidio" mission. Afterward, you can purchase it at the Escalara Gunsmith for $750.
The Buffalo Rifle is yours after you complete the level 5 Master Hunter Challenge. You can then buy it at any gunsmith for $475.
To get the Evans Repeater, simply buy it from the gunsmith in Blackwater.
The Henry Repeater will take a bit of effort to unlock, as you'll have to clear the Nosalida Hideout to do so.
As your reward for completing the "New Friends, Old Problems" mission, the Repeater Carbine will be unlocked.
To get the Springfield Rifle, you'll have to either wait until you complete the "We Shall Be Together in Paradise" mission, clear the Gaptooth Breach Hideout, or just buy it from the Thieves' Landing Gunsmith for $300.
Finally, the trusty Winchester Repeater can be unlocked by either Completing the "Spare the Rod, Spoil the Bandit" mission or purchasing it from the Armadillo Gunsmith for $350.