Floating-Harbor Syndrome: Symptoms And Description
Discovered in 1973 by Pelletier and Feingold in a patient admitted at the Boston Floating Hospital, Floating-Harbor syndrome, also known as the Pelletier-Leisti syndrome, is a very rare genetic disorder that is typically characterized by short stature, delayed speech development and a unique facial appearance.
It was named after the first two identified patients from Boston Floating Hospital and Harbor General Hospital respectively. It is a very rare disorder and to date, only twenty confirmed cases have been recorded. Since it is so rare, it has a prevalence rate of 1 in 200,000 people in the United States.
It is characterized by a variety of symptoms that include: short stature, delayed expressive language skills, delayed speech development, delayed bone growth and a triangular face which becomes more prominent with age. Patients have a broad nose, deep-set eyes and a rather wide mouth with thin lips which give a striking Facial appearance.
Other features of Floating-Harbor Syndrome are low birth weight, intrauterine growth retardation, feeding issues, hyperkinetic behavior, the exhibition of clubbed fingers and excessive body hair with long eyelashes, dental problems, learning limitations, gluten intolerance, constipation, pulmonary stenosis, lack of philtrum, tiny and deep-set nails, dysplastic hips, a high-pitched voice and cataracts.