Imuran and Breastfeeding
It has been found that if a woman is on medication then during breastfeeding, Imuran is passed through breast milk. Since there are various side effects in the infant, manufacturers recommend that women should not take this medicine when nursing. In case, a woman takes this medicine while breastfeeding, she needs to talk to the healthcare professional about the kind of risks associated with it.
According to the U.S. Food and Drug Administration (FDA), there is a specific category system that classifies the possible risks to a fetus when a certain kind of medicine is taken during pregnancy. This is called Category D. Imuran falls into this same category. The Category D medicines pose risks to the fetus, but, such medicines may be given to pregnant women if the healthcare provider believes that the benefits to the mother are greater than the possible risks to the unborn child.
Scientists used animal models such as pregnant rabbits and mice to find the possible risk of birth defects and they found that the drug increases the risks such as skeletal and organ problems on the fetus. And in humans, many infants were born with poorly functioning immune systems.
While the drug should be avoided for the treatment of rheumatoid arthritis during pregnancy whenever possible; there are situations when it is the best drug to help ensure the woman's health, such as when Imuran is used to stop kidney transplant rejection.