Loneliness as a genetic disease can have dire effects on a person. It has been linked to many emotional problems and mental conditions, such as anxiety and a lack of self-esteem. Loneliness also can result in feelings of irritability, anger and a further lack of social interaction. Physically, loneliness has been linked to an increased chance of heart disease.
According to the University of Chicago, studies have shown that people who experience loneliness generally marry people who feel lonely and vice versa for non-lonely people. This may further propagate the factors of these conditions in reproduction.
In order to combat feelings of loneliness, most medical professionals suggest increased social networks. Due to the origins of the genetics, it is believed that strong friendships cause a decrease in feelings of loneliness; however, there is a link to people with social skill factors, such as introversion to loneliness, which may impact this solution.