Signs and Symptoms of Marfan Syndrome
Marfan syndrome is present at birth, but symptoms may appear later in life. It mainly affects the connective tissue of the body, and the degree of symptoms may vary from patient to patient.
People with Marfan syndrome tend to be tall and have thin skeletons. Arms, legs, fingers, and toes are disproportionately long relative to the rest of the body, and bones and joints may become brittle.
Marfan syndrome may also cause the formation of defective connective tissues in the heart, blood vessels, eyes, or lungs.
In the heart the genetic disorder affects the valves and produces mitrial valve prolapse. As a result a patient will experience shortness of breath, tiredness, and palpitations.
If the eyes are affected objects can appear blurred, there's dislocation of the lens and changes in the shape of the eye.
In blood vessels Marfan syndrome causes dilatation of the arteries, which can rupture, resulting in a life-threatening condition. Principally the aorta is affected, the main artery that supplies blood from the heart to all other parts of the body.
When the lungs are affected, bronchitis, pneumonia, and emphysema may result.