The Endoplasmic Reticulum

Written by:  • Edited by: Paul Arnold
Updated Sep 25, 2009
• Related Guides: Endoplasmic Reticulum

The endoplasmic reticulum is a specialized sub-cellular structure within eukaryotic cells. In this article we'll find out more about its functions, and where it is located.

Introduction

The endoplasmic reticulum or ER is a sub-cellular structure which performs several specialized tasks within the cell; hence it can be classified as an organelle. It is formed out of several interconnecting tubules and vesicles. The ER does not function in isolation, but coordinates with several other organelles. Endoplasmic reticulum functions include involvement in drug metabolism, production of steroids, storage of glycogen, facilitating the transport of proteins and protein folding.

In case you are interested in history, the ER was first officially seen by a team of biologists consisting of Keith R Porter, Albert Claude, and Ernest F Fullam and published in the year 1945 in a paper in The Journal of Experimental Medicine.

Type of Endoplasmic Reticulum

There are different types of ER found in complex cells namely smooth endoplasmic reticulum and rough endoplasmic reticulum. They differ not only in their physical appearance but in the way they function as well.

The smooth ER usually resembles a set of smooth tubes and it mainly acts as a storage point for steroids as well as ions. Both these substances have important functions in the cell activity. Sometimes there may be an immediate need for ions and they are supplied by the smooth ER in such a situation. There is also a special type of smooth ER which is known as the sarcoplasmic reticulum and though it is much similar to the normal smooth ER, its main difference lies in the fact that it is used to store calcium ions which are released upon muscle simulation.

The rough ER looks more like bumpy sheets rather than smooth tubes. They have ribosomes studded to them, and their main function is the manufacturing and packing of proteins. It must however be noted that the ribosomes are not permanently attached to these rough ERs, they adhere when protein manufacturing has to be carried out. After this process is complete the protein is then transferred on to the Golgi apparatus or the membrane of the cell via vesicles.

Where is the endoplasmic reticulum located? There is not one fixed point where the ER can be said to be concentrated since it forms a network of membranes and these are found throughout the cell. Also it is not necessary that the ER of various cells would look the same - they could be different based on their exact role in the cell. The sketch below shows the endoplasmic reticulum and the small dots represent the ribosomes that are studded to it.

The Endoplasmic Reticulum

The Endoplasmic Reticulum

Comments

Showing all 8 comments
 
Parnoti & Mayuri Jul 19, 2011 9:32 AM
ER
I am very thankful to you for this.
James Sep 13, 2010 11:38 AM
Thanks.
This has helped me alot with my AS work, needed to write about the function of Rough Endoplasmic Reticulum, Thanks.
varun,R Sep 3, 2010 5:08 PM
Endoplasmic Reticulum
ya its fine if there is more about molecular aspect and function of ER it would me some more nice
tina arora Aug 14, 2010 10:15 AM
endoplasmic reticulum
this article helped me a lot in studing about endoplasmic reticulum.
myalsubaiy May 30, 2010 3:18 PM
Endoplasmic reticulum
useful and important subject
jake May 30, 2010 4:18 AM
RE: The Endoplasmic Reticulum
very good information
Dr.Mohamed AL-Subaiy Mar 17, 2010 9:51 AM
cytology
The subject is very important and useful
nur Dec 5, 2009 12:35 PM
very good in explanation and structuring the subject
keep in good working. link to you in my blog, http://pearlofiman.blogspot.com. thank you much for the information. really help me as a medical student
 
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