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There are two key methodologies used in Six Sigma projects, one for dealing with existing processes and another for implementing new processes.
DMAIC is an acronym for Define-Measure-Analyze-Improve-Control, the five Six Sigma components that are utilized in a project designed to improve existing practices.
Likewise, DMADV stands for Define-Measure-Analyze-Design-Verify, the steps taken in the creation of a new product or service design. DFSS, or Design for Six Sigma, is simply another name for the DMADV process.
If you would like to explore these Six Sigma components in more detail, Natasha Baker’s article Key Concepts of Six Sigma and this document offered by the Carnegie Mellon Software Engineering Institute are great places to start.