Figure out how you use them most. Are you looking for blog topics? Do you need to research a topic? Do you want to catch up on the major news for the day without using a newspaper?
With that done, the next step is to organize your feed reader. Are you using Outlook to read RSS feeds? Whether you use a feed reader application, Outlook, or browser -- most come with folders or a way to customize how you organize the information and feeds. You might create folders by topic, by client, by project, or by interest. Need a laugh a day? Create a folder with humorous feeds. Want your daily news? Create a folder called "Daily News" to contain only feeds you want to read every morning rather than feeds from every news site in the world. Then you'll never get work done. This type of folder should have few feeds with your absolute favorites.
A search feature comes in handy too. Most feed readers have a search feature and this helps you look for only what you need without scanning headlines and folders.
Now that you're organized and ready to dig in your feeds, figure out what you need from them now before opening them. As soon as you have reached your goal with the feed reader, close it. You have work to do and no one to tell you to stop reading news.