Organization of the Page & Printing
For most desktop publishers with limited page layout experience, it's best to follow the "rule of thirds." Either mentally or using your desktop publishing software, divide your page into thirds both vertically and horizontally. This will help you determine where to place your most important information. Typically, important information should be placed in the upper or lower third of the page, or at any of the four points where your thirds intersect.
Arrange your information - starting with the most important - by following a "Z" or "backwards 'S'" format. This follows the readers' general inclination to read from left to right and then zig-zag from the right end of one line to the left end of the next line.
When creating titles and body copy, it's best to use variations of only one or two fonts - three at the most. Using the same fonts in the same color (usually black) with varying weights of boldness and size create continuity in the layout.
Alignment is another key to good layout organization. Make sure the alignment of your text is consistent throughout by creating margins and following alignment guides offered by your desktop publishing software.
While graphics, photos and other art add good visual appeal, only use them if they are important to the piece. Gratuitous graphics only create unnecessary clutter on the page and may creating printing issues for the reader.
Sometimes, the best graphic is no graphic at all. Make sure your document has a good balance between information, graphics and white space to ensure the document isn't too busy-looking so that users can easily print your project.