If you're searching for a job within the same occupation as the last job you held – or in the one you're still working – then you might be able to take tax deductions. Job seekers looking to change careers are out in the cold, sorry. The “same occupation rule” rules you out.
The same occupation rule is determined by the nature of the work, not by the job title or industry. For example, if the last job you held was general manager for a small manufacturing company, then division manager in a larger manufacturing company may qualify. However, marketing manager will probably not, even if it's in the same industry. If you take a temporary interim job as a waiter or grocery clerk to pay the bills while you're job hunting, you should still be able to deduct expenses.
If you're fresh out of school, then you can't deduct any tax expenses, since by definition you're starting a new career…even if you worked in your chosen field during your graduate studies, you're probably looking for a job with more responsibilities now that you have a degree.