The decline in the stock market resulted in the inability of investors to repay their loans. This default in the financial markets is what had such a butterfly effect on the economy, since the losses of the 16 percent of US households were invested in the stock market would not by themselves have wreaked such economic choas. Banks went under and millions lost all of thier deposits. Many companies went bankrupt. Access to credit was limited and people lost their jobs until over 25 percent of American adults were unemployed. In turn, consumer spending was depressed. As a result, companies received less revenue, people were laid off, and, eventually, those companies too went bankrupt.
Many nations took steps to protect thier domestic industries during the crash. The USA passed the Smoot-Hawley Act which heavily taxed imports to spur purchases of American-made goods. However, since all of the USA's trading partners immediatly passed similar laws, our export market dissapeared overnight. International Trade dropped by 50 percent during the crash.
The international economic difficulties caused by the Great Depression contributed to the rise of the Nazis in Germany, and compelled Imperial Japan to inveade China for acccess to her markets and resources, so in a way it can be said to have set the stage for WW2.