The main focus of iMafia II PlayMesh Points, as well as PlayMesh Points for all other PlayMesh games, should be for adding mafia members. Mafia members gradually get more and more expensive as you go through iMafia II, and you need them to control properties, complete missions and win fights. Later in iMafia II mafia members are going to be the most expensive part of the game without any close parallel. This means that you really should use almost all of your PlayMesh Points on mafia members. If you are very far ahead in iMafia II mafia members, then use your PlayMesh Points on free money, especially early on when you are avoiding leveling up.