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Aside from support for multiple Twitter accounts,
Seesmic for Android also boasts several great features that would it your favorite Twitter app for your Android devices. Here are some of my favorite features of Seesmic for Android.
Background Notification - I maintain two Twitter accounts. One is used for communicating with my close friends as well as for monitoring Twitter users who are not in the technology field. I maintain this account as clean and less noisy as possible. My other Twitter account is for my technology and blogging contacts. This account's followers have blown out of proportions with so many of them I don't really know. Much as I would like to unfollow this people, I could not because some of the auto-generated links they tweet can be useful most of the time. Using Seesmic with these two Twitter accounts enable me to configure what notifications I want to receive on my Nexus One Android device. I could even set a specific ringtone for specific notifications - that is one ringtone for tweets, one ringtone for replies, and so on. It's like your usual SMS alerts wherein you'd know immediately whether a new update is important or not.
Unified Twitter Timeline - While notification alerts can be distinguished from each other, if you're browsing your Twitter account, Seesmic lets you browse all your timelines in a single, simple screen. Whether you want to scroll through your friends' timelines or want to look for a DM sent to you, Seesmic's interface allows you to do so in just a tap on the screen.

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Clear Profile Information - There may be times when you need to manage your Twitter followers or following list even while on the move. Seesmic allows you navigate through contacts' profile from the timeline. You simply tap on the user's avatar or screen name and you will be brought to the user's profile to see his tweets, favorites, following, and followers. And from there you can simply go back to your own Twitter timeline.
Focus on Content - Another great feature of Seesmic that makes it as great Android software for Twitter to manage friends list is the way it focuses on tweets. All the main actions that you can do for a tweet are accessible on the main screen, while all other actions are accessible via the Option Menu. Seesmic lets you focus on replying to tweets as well as posting your own tweets easily.