Click the Call key on your Blackberry Device (The Green Button) at which point you'll be taken to your phones dialer program. From the dialer screen click the Blackberry Menu key, then scroll down and select Options.
After you click options you'll see the following screen: (Click To Enlarge)

click to enlarge
Simply scroll down to call forwarding and click on that choice. You'll then be presented with a phone number options screen. On this screen you'll see the ability to disable calls with an option called "Do Not Forward" along with three forwarding options which include: "If Busy" , "If No Reply" and "If Not Reachable" you have the option to input one phone number for all options or a different number for each option. If you want certain calls forwarded to a secretary of different line these options are the best way to accomplish that goal.
Here's a screenshot of the Call Forwarding Menu:

click to enlarge
To access the number change option simply click your Blackberry Menu from the screen shown above and then select "New Number" or "Edit Numbers."
After you enter the numbers you want to use your Call Forwarding Application will be activated and new calls will be forwarded to the phone numbers you've entered into the list found above.