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To use Yahoo Pipes, you will need a Yahoo account. If you do not already have one, you can sign-up here. After login, you will be able to immediately start using Pipes.
Yahoo Pipes relies on modules to operate. This makes usability fairly simple. All modules are located along the lefthand side of the Pipes homescreen. Simply drag a module onto the main screen, or canvas. From there, click the bottom button on the module, and drag it towards the output module. This will automatically create a Pipe, linking the two modules together. Click on the options portion of the main module, and customize.
The only information you need to use most Yahoo Pipe modules is the feed url of a site. From there, Pipes will do all the information moving for you.
If you are interested in getting started with Yahoo Pipes, you can visit the official site.