The information on this report is very valuable to you in regards to the success of your website. For instance, if you notice the entrance page is the same as the exit page, you know people are not staying on the site long enough to look around. If you notice people leaving from the home page, you may want to make some changes, because chances are they aren't viewing many other, if any, parts of the site.
If you see a large percentage of the exits coming from the same page, logically where you want to see your visitors leaving the site, you are doing something right and should not change too much around. The thing to remember is any changes may adversely affect your site metrics, just as any change may improve them. Carefully alter the site based on what research tells you needs to be done, changing one thing at a time until you are sure you have pinpointed the cause of the negative trend.
Pay close attention to your advertising to see if it is affecting the page people are coming in on, as this can also affect the page people decide to leave on.