The garden variety of anemia is defined as a deficiency of red cells or of hemoglobin in the bloodstream leading to weariness and fatigue. Pernicious anemia differs in its specific cause and method of onset—a lack of the water-soluble vitamin, B12 (cobalamin), and the damage it can do. Pernicious anemia generally goes undetected until the sufferer is in his or her thirties. This slowly perceived onset is implied by the word pernicious, which means to have a harmful affect in a gradual or subtle way. How is the disease diagnosed and how successfully treated? Read informative Bright Hub articles to find out.
Red Blood Cells: Credits: NIH Clinical Center