In short, the answer to this question is No! All windows and outside doors should be shut whilst the air conditioning is operating for the following reasons:
1. Air conditioning systems are specifically designed, sized and installed to distribute the correct quantity and quality of air to the home. Leaving a window open will affect the loading of the A/C unit.
2. The efficiency of the home air conditioning unit depends on the system of fans and ducting being carefully balanced, normally by a professional HVACR engineer. Leaving a window open will alter these settings, lowering the system’s efficiency.
3. As can be seen from my diagram, on modern A/C systems an air filter and/or an air purifier are incorporated in the discharge ductwork. The filter is imperative to remove dust particles or pollen, whilst the purifier can have a UV/catalyst that removes any chemicals or odors. These components are essential if anyone in the family suffers from allergies such as hay fever or asthma. Leaving a window open will introduce dust/odors/pollen from the garden into the house and into the air conditioning system.
4. The de-humidifier removes the moisture from the airstream. This prevents dampness, condensation and damage to electrical appliances and electronics. It also makes the living quarters more comfortable for the family. Leaving a window open will reintroduce moisture to the system and home.
Reference Webs.
- Energystar: HVACR recommended practices
- Progressenergy: HVACR energy saving tips
- Associatedcontent: operating air conditioning efficiently
- articlebase: sequence of operation of an AC unit
Related: What is the Best Indoor Humidity Range for Books, People, and Electronics?