Microsoft offers a disk cleaner that isn't very efficient for removing temporary files. Several freeware and open source applications are available on the internet that are much more efficient.
CCleaner
CCleaner (by Piriform) is one of the best utilities made to clean both your registry and temporary files from your computer. (BrightHub Article) CCleaner cleans all major Browsers including Google's Chrome, Safari, Opera, Internet Explorer and Firefox. CCleaner also cleans the recycle bin, the clip board, Windows temp files, application temp files and dozens of other areas.
Glary Utilities
Glary Utilities is a new comer to the cleanup arena and offers an excellent program that offers a 1 click cleaning of your computer that cleans internet files, temporary files and the registry. (BrightHub Article)
Comodo
Comodo recently released an excellent cleaner that cleans all major operating systems including Windows Server. Comodo provides both 32 bit and 64 bit versions that clean all areas of your hard drive including the registry. With their safe file deletion and systematic backup, changes are not committed until after a reboot by the user. (BrightHub Article)

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