Using Yahoo Anti-Spy
You can always run CA anti-spyware, even if the browser is closed. Simply browse the Program folders in Windows and find the CA Yahoo! Anti-Spy directory. If you are using Vista or Windows 7 with UAC enabled, run CAYahooAntispy.exe with elevated permission by right-clicking the executable and select "run as administrator."
There's an option to manage quarantined and allowed items that the anti-spyware has detected, and you can configure it to check for updates, scan for tracking cookies and scan the computer as soon as you open the anti-spyware program for Yahoo toolbar users.
Note that Yahoo anti-spyware or CA Anti-spy can detect adware, backdoors, Browser Helper Objects, DDoS, dialers, downloaders, firewall killers, hijackers, hostile ActiveX, hostile Java, hostile Scripts, IRC Ware, keyloggers, password capture tools, Remote Access Tools (RATs), non-commercial spyware, Trojans and worms but it cannot detect viruses and hacking tools because it is not an anti-virus program but a free anti-spyware or anti-malware program.
Note: The anti-spyware will only run a quick scan on the computer and will only offer a full system scan if the quick scan has found threats.
The screenshot below is an example of a detection by CA Yahoo Anti-spyware, when I infected my computer with spyware program Trojan Zbot. The filename is bot3.exe and it is detected by many malware scanner vendors (see Jotti online scan result). The quick scan found threats added by bot3.exe, so the scanner offered a full system scan for the PC:
The scanner correctly detected the location of the malware on the PC:
Yahoo toolbar with anti-spy will remove the detections, free-of-charge. Yahoo spyware remover downloads all updates for the anti-spyware by CA for free as well. You should use this program if you need an on-demand scanner while you use the resident protection of another anti-virus program such as AntiVir 10, AVG, Avast or Microsoft Security Essentials.
Image credit: Screenshot taken by the author.