BitLocker is a driver encryption utility that allows you to encrypt any drive, including boot sector, system area, or any other removable devices like USB drives. In windows explorer, right click the drive you want to encrypt and BitLocker will provide you a combination of security measures like PIN, smart card, password and TMP (Trusted Platform Module) chip to encrypt the drive. It supports all types of volumes like FAT, FAT32, NTFS and Extended Fat.
However, you should be cautious while using BitLocker because if you forget the password, BitLocker will scramble your device. It’s better to backup your data in some other media before encrypting the drive.