In my testing utorrent on Ubuntu Linux via WINE worked just as well as the utorrent beta available natively for Mac OS X. I downloaded several large torrents with excellent speeds and the resulting files worked fine. All basic functions that I use worked as well, this includes port forwarding, DHT, pre-allocating files and setting upload and download limits.
Using utorrent on Ubuntu Linux via WINE is fundamentally the same as using utorrent on Windows (after all you are running the Windows version). Menus are in the same place and you have the same options available that you would if you were running utorrent natively in Windows. As with all Windows programs you run in Linux via WINE you may encounter some odd behaviour that you would not see on a native platform.