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The first thing you should do is makes sure everything is plugged in properly. With the standard 1/8” audio jack cables, they do sometimes causes static interference if not plugged in all the way. Check your speaker connection, which is usually located on the back of a desktop, and make sure it is pushed in. You could even take the cable out, wipe it off with a soft cloth, and then stick it back in there. Sometimes rotating it around in the hole will help, too. It might be a fingerprint or dust that is causing the connection to get interrupted and therefore making static sounds come out of your speakers.
In my experience, one of the more common causes for speaker static is electrical interference. Make sure your speaker wires are not running across any power cables. I know sometimes this is hard to do when you have a big jumble of cables behind your computer. Even in that mess, try to make sure your speaker wire isn’t coiled around the computer’s power cable, or any other cable for that matter. Also make sure it doesn’t have any knots or kinks that could disrupt the signal that travels down the thin wires inside. Desktop lamps can also interfere with the speaker, so make sure those lamp wires are also out of the way.