EVGA P55 FTW200
There are limited reasons that one might want a high-end P55 motherboard, eventually it makes more sense to go all the way to X58. But if you're looking for the best of the middle-ground, it would be wise to consider EVGA. EVGA has a reputation as one of the best gaming-oriented hardware manufacturers, much of which they earned by putting out a board for Nvidia's 680i, a chipset beloved by enthusiasts and gamers, that could go up against the best Asus and Gigabyte had to offer. The P55 FTW200 is another example of a great, gamer-focused, product. It is loaded with every feature one could want. This includes not only the overclocking and power-management features found in other boards on this list, but also a tri-BIOS configuration that allows for maximum protection against BIOS corruption, LED CPU temperature readouts, a clear CMOS button, and jumpers to disable PCIe slots and help configure SLI setups.
The EVGA P55 FTW200 also includes the special nForce 200 SLI chip, which provides 32 PCIe 2.0 lanes (but only when using Nvidia cards). This means it can run two cards in SLI at full x16 speed or three at speeds of x16/x18/x8. This makes it clearly better for hardcore gamers than other motherboards, as P55 motherboards without this chip only have enough PCI bandwidth to run one card at full x16, having to split lanes for dual-cards to x8/x8 and triples to x8/x4/x4. Crossfire does not gain the advantages of the chip, but can still be used.
These are features that only an enthusiast could love, and are well in excess of what most will need, and the features cause the P55 FTW200 to retail at $300 dollars. At that price a X58 motherboard is a viable alternative. This motherboard is best for high-end gamers, but workstation users will appreciate the triple-channel memory and upcoming support for upcoming Core i9 processors offered by the X58 chipset.